What Is Karachi HPMC?

What Is Karachi HPMC?

Hydroxypropyl methylcellulose (HPMC) is a nonionic cellulose ether with a high tensile strength and viscosity.karachi hpmc It is soluble in polar organic solvents and has good film-forming properties. HPMC is also biocompatible, making it a safe choice for pharmaceutical formulations. It is also an ideal binder for tablets and other dosage forms. Its low cost makes it an attractive alternative to other expensive pharmaceutical excipients.

HPMC is a biodegradable and biocompatible polymer that can be used for many applications, including drug delivery, cosmetics, dyes and paints, and adhesives.karachi hpmc Its biocompatibility and excellent water solubility make it a popular choice for food applications, where it can be used to make films for packaging purposes. Its high viscosity and tensile strength make it an effective disintegrant for tablet formulations. It is also useful for coating paper, leather, and ceramics.

Different viscosity grades of karachi hpmc have varying physical and chemical properties, which makes them suitable for different formulations.karachi hpmc For example, HPMC K4M has a lower molecular weight and viscosity than HPMC K100M. It is also cheaper than K100M.

The hydroxypropyl methylcellulose is a naturally occurring biodegradable polymer that has the potential to replace a variety of synthetic plastics.karachi hpmc It can be dissolved in a wide range of organic solvents and has a high tensile strength, making it an excellent choice for pharmaceutical products. It can also be used as a filler and binder to help tablets keep their shape. It can also be used to improve the taste of drugs that contain sugars.

It is important to note that hydroxypropyl methylcellulose side effects are relatively rare.karachi hpmc However, it is important to monitor any symptoms you might experience. If you notice any side effects, talk to your doctor about them. If the symptoms are severe, contact a medical emergency service right away.

In addition, hydroxypropyl methylcellulose is biodegradable and soluble in both aqueous and polar organic solvents. It can be mixed with a wide range of ingredients to produce a variety of formulations. It is also available in various forms, including flakes and powders. The flakes and powders can be added to a variety of formulations, such as topical creams, gels, and sustained-release tablets.

The toxicity study of the fabricated HPMC-pectin-co-acrylic acid hydrogels was performed in albino rabbits as per Organization for Economic Cooperation and Development (OECD) guidelines. Twelve albino male rabbits were divided into two groups named as controlled and tested group respectively. They were fed with healthy food and water on a daily basis. All the procedures were performed according to the OECD guidelines and approved by Institutional Research Ethics Committee of Faculty of Pharmacy, The University of Lahore notification no. IREC-2019-100. The samples were accurately weighed in aluminum pans and hermetically sealed. The fabricated hydrogels were prepared by wet granulation technique. Samples (5 mg) of LVF, HPMC K4M, PVP, physical mixture of LVF with HPMC K4M and mixture prepared by wet granulation technique of LVF with HPMC K100M using PVP as binder were hermetically capped and stored at room temperature in air-tight condition.

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